Exhaust seen on American car (4)
I believe the answer is:
tire
'exhaust' is the definition.
(synonyms)
'on american car' is the wordplay.
'on' is a charade indicator (letters next to each other).
'american' becomes 'ire' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'car' becomes 't'.
'ire' after 't' is 'TIRE'.
'seen' acts as a link.
Can you help me to learn more?
(Other definitions for tire that I've seen before include "Weaken" , "Become exhausted" , "Flag" , "Exhaust" , "Grow weary of rithe" .)