Exotic Persia trip? No sweat (12)
I believe the answer is:
perspiration
'sweat' is the definition.
('perspiration' can be a synonym of 'sweat')
'exotic persia trip? no' is the wordplay.
'exotic' indicates anagramming the letters.
'persia'+'trip'+'no'='persiatripno'
'persiatripno' anagrammed gives 'PERSPIRATION'.
(Other definitions for perspiration that I've seen before include "is exuded" , "Ninety nine percent of genius" , "Sweat" .)