Expatriate chucked up life-prolonging concoction (English not Irish) (5)
I believe the answer is:
exile
'expatriate' is the definition.
(I know that expatriate can be written as exile)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for exile that I've seen before include "eg Napoleon on Elba" , "Get rid of" , "being always away from home" , "Throw out" , "One barred from their native country" .)