Explode some powder up there (5)
I believe the answer is:
erupt
'explode' is the definition.
(erupting is a kind of exploding)
'some powder up there' is the wordplay.
'some' indicates the answer is hidden within the clue (some of the parts of the word are used).
'ERUPT' is hidden in the letters of 'powder up there'.
(Other definitions for erupt that I've seen before include "Discharge" , "go up" , "What canines do" , "Break out suddenly and violently" , "be active" .)