Expression of disgust in Brighton and Hove, first of all (3)
I believe the answer is:
bah
'expression of disgust' is the definition.
(as in 'bah humbug!')
'brighton and hove first of all' is the wordplay.
'first of all' says to take the initial letters.
The first letters of 'brighton and hove' is 'BAH'.
'in' acts as a link.
(Other definitions for bah that I've seen before include "''... Humbug'' Scrooge's cry" , "Comic expression of contempt" , "Exclamation of contempt or disgust - Scrooge used to say it" , "''...! Humbug!'' (Scrooge)" , "Disbelieving expression" .)