Extract spinal lesion altogether (2,3)
I believe the answer is:
in all
'altogether' is the definition.
(synonyms)
'extract spinal lesion' is the wordplay.
'extract' indicates a hidden word (I've seen 'extract of' mean this (I've seen this in other clues)).
'IN ALL' is hidden within 'spinal lesion'.
(Other definitions for in all that I've seen before include "Everything considered" , "totally" , "Taking everything into account" , "With everything counted" , "Altogether" .)