Extreme fatigue from the anxious preparation (10)
I believe the answer is:
exhaustion
'extreme fatigue' is the definition.
'exhaustion' can be an answer for 'fatigue' (exhaustion is a kind of fatigue). I'm unsure of the 'extreme' bit.
'the anxious preparation' is the wordplay.
'preparation' indicates anagramming the letters.
'the'+'anxious'='theanxious'
'theanxious' with letters rearranged gives 'EXHAUSTION'.
'from' acts as a link.
Can you help me to learn more?
(Another definition for exhaustion that I've seen is " fatigue".)