Extremely ticklish open garments made of leather? (6)
I believe the answer is:
thongs
'made of leather?' is the definition.
(a thong is a piece of leather)
I can't explain the rest of the clue.
(Other definitions for thongs that I've seen before include "Leather strips on a whip" , "Flexible leather strips on whips" , "Skimpy undergarments" .)