Facing long interruptions, she's bored of nasty European city (6)
I believe the answer is:
lisbon
'european city' is the definition.
(capital of Portugal)
'facing long interruptions she's bored of nasty' is the wordplay.
I cannot quite see how this works, but
'long' could be 'l' and 'l' is located in the answer.
'of' could be 'o' and 'o' is present in the answer.
The remaining letters 'isbn' is a valid word which might be clued in a way I don't see.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for lisbon that I've seen before include "European capital" , "Portuguese capital" , "Capital city and Treaty" , "Capital city on the Tagus" , "Capital of Portugal" .)