Fail to meet American woman, colloquially speaking (6)
I believe the answer is:
missus
'woman colloquially speaking' is the definition.
I can't judge whether this definition defines the answer.
'fail to meet american' is the wordplay.
'fail to meet' becomes 'miss' (I've seen this before).
'american' becomes 'US' (United States).
'miss'+'us'='MISSUS'
Can you help me to learn more?
(Other definitions for missus that I've seen before include "Dutch American" , "Wife (informal)" , "As partner" , "trouble and strife" , "Wife (colloquial)" .)