Failing internally, ill orang is stricken in consequence of eating wrong fruit (8,3)
I believe the answer is:
original sin
'consequence of eating wrong fruit' is the definition.
(Adam and Eve eating the forbidden fruit)
'failing internally ill orang is stricken in' is the wordplay.
I cannot quite understand how this works, but
'failing' could be 'sin' (I've seen this in another clue) and 'sin' is present in the answer.
'in' is found in the answer.
This may be the basis of clue (or it may be nonsense).
(Other definitions for original sin that I've seen before include "Supposed innate tendency to evil" , "that's supposedly everyone's fault?" , "It ruins us all" , "Man's innate offence" , "Tendency to go astray" .)