Falls for a redhead once more, getting uplifted (7)
I believe the answer is:
niagara
'falls' is the definition.
(thesaurus)
'a redhead once more getting uplifted' is the wordplay.
'redhead' becomes 'r' (the head/first letter of 'red').
'once more' becomes 'again' ('again' can be a synonym of 'once more').
'getting' says to put letters next to each other.
'uplifted' says the letters should be written in reverse.
'a'+'r'+'again'='aragain'
'aragain' in reverse letter order is 'NIAGARA'.
'for' acts as a link.
(Other definitions for niagara that I've seen before include "Waterfall at Iran aga" , "River flowing from Lake Erie into Lake Ontario" , "Famous waterfall" , "Great falls on border of Canada and USA" , "North American waterfall" .)