Fashion designer Klein (4)
I believe the answer is:
anne
'fashion designer klein' is the definition.
(I've seen this in another clue)
This is all the clue.
(Other definitions for anne that I've seen before include "Last Stuart monarch, d. 1714" , "- - of Cleves" , "She married Shakespeare" , "British queen" , "One of the Bronte' tens" .)