Fashion shown by nurse hosting queen (5)
I believe the answer is:
trend
'fashion' is the definition.
(thesaurus)
'nurse hosting queen' is the wordplay.
'nurse' becomes 'tend' (I've seen this before).
'hosting' is an insertion indicator.
'queen' becomes 'r' (r is abbreviation regina. e.g. in ER ).
'tend' placed around 'r' is 'TREND'.
'shown by' is the link.
(Other definitions for trend that I've seen before include "General direction in which something is developing" , "Bias" , "Prevailing tendency" , "Med. port, taken by Crusaders" , "Style, vogue" .)