Fashionable craft set off for lifeless area (7)

I believe the answer is:

infarct

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'lifeless area' is the definition.
The answer and definition can be both states of affairs as well as being singular nouns.
Maybe they are linked in a way I don't understand?

'fashionable craft set off' is the wordplay.
'fashionable' becomes 'in' (in can mean fashionable or trendy).
'set off' indicates an anagram (letters made to move or set off).
'craft' anagrammed gives 'farct'.
'in'+'farct'='INFARCT'

'for' acts as a link.

Can you help me to learn more?

(Another definition for infarct that I've seen is " Dying tissue".)

I've seen this clue in The Daily Express.

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