Fate in Tyneside not completely appalling (7)
I believe the answer is:
destiny
'fate' is the definition.
(synonyms)
'tyneside not completely appalling' is the wordplay.
'not completely' means to remove the last letter.
'appalling' indicates anagramming the letters (an appalling spelling).
'tyneside' with its final letter removed is 'tynesid'.
'tynesid' is an anagram of 'DESTINY'.
'in' is the link.
(Other definitions for destiny that I've seen before include "Kismet, fate" , "must?" , "Lot" , "The future as arranged by fate" , "Fortune" .)