Father pinching female is frustrated (6)
I believe the answer is:
dashed
'is frustrated' is the definition.
(I've seen this before)
'father pinching female' is the wordplay.
'father' becomes 'dad' (dad is a kind of father).
'pinching' means one lot of letters goes inside another (taking inside).
'female' becomes 'she' (I've seen this before).
'dad' going around 'she' is 'DASHED'.
(Other definitions for dashed that I've seen before include "Ran quickly, rushed" , "Darted headlong" , "completely destroyed" , "hurled at" , "Jolly" .)