Fatty Arbuckle's coat worn by alkie having taken hem up a little (7)
I believe the answer is:
adipose
'fatty' is the definition.
(synonyms)
I don't understand the rest of the clue.
Can you help me to learn more?
(Other definitions for adipose that I've seen before include "Of tissue, fatty in substance" , "Relating to fat" , "I soaped up with fatty kind of tissue" , "Containing fat" , "Relating to fatty tissue" .)