Feel so loveless and misguidedly seen (5)
I believe the answer is:
sense
'feel' is the definition.
(I know that feel can be written as sense)
'loveless and misguidedly seen' is the wordplay.
'loveless' becomes 's' (I can't justify this - if you can you should believe this answer much more).
'and' says to put letters next to each other.
'misguidedly' indicates an anagram.
'seen' is an anagram of 'ense'.
's'+'ense'='SENSE'
'so' acts as a link.
Can you help me to learn more?
(Other definitions for sense that I've seen before include "Feel intuitively" , "Detect, be aware of" , "Nous" , "Feel, perceive" , "eg Taste, smell" .)