Feeling of uneasiness (7)
I believe the answer is:
malaise
'feeling of uneasiness' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for malaise that I've seen before include "Feeling of physical or mental illness" , "depression" , "Disquiet" , "Feeling of illness or mental uneasiness" , "Unease; lethargy" .)