Feels the loss of the company of young ladies? (6)
I believe the answer is:
misses
This clue is a double definition.
'feels the loss of' is the first definition.
(miss can mean to feel something's loss)
'company of young ladies?' is the second definition.
(people referred to as 'miss')
'the' acts as a link.
(Other definitions for misses that I've seen before include "Lacks; lasses" , "Fails to hit the target" , "Overlooks" , "Unsuccessful attempts" , "young women" .)