Fellow in desperate tangle with men (9)
I believe the answer is:
gentleman
'fellow' is the definition.
(I've seen this before)
'desperate tangle with men' is the wordplay.
'desperate' is an anagram indicator (I've seen this in other clues).
'with' means one lot of letters go next to another.
'tangle' put after 'men' is 'mentangle'.
'mentangle' anagrammed gives 'GENTLEMAN'.
'in' is the link.
(Other definitions for gentleman that I've seen before include "Male of refinement" , "Polite, kind or upper-class fellow" , "trustworthy type" , "A man of refinement" , "Courteous fellow" .)