Female pointer to produce litter (6)
I believe the answer is:
farrow
'litter' is the definition.
(farrowing is a kind of littering)
'female pointer' is the wordplay.
'female' becomes 'f' (abbreviation).
'pointer' becomes 'arrow' (synonyms).
'f'+'arrow'='FARROW'
'to produce' is the link.
(Other definitions for farrow that I've seen before include "pig production" , "Give birth to piglets" , "Little piggies" , "Actress" , "Produce piglets" .)