Female priest, a senior manager (8)
I believe the answer is:
director
'a senior manager' is the definition.
(eg company director)
'female priest' is the wordplay.
'female' becomes 'di' (short for Diana).
'priest' becomes 'rector' (I've seen this before).
'di'+'rector'='DIRECTOR'
(Other definitions for director that I've seen before include "Company board member" , "Controller of production or member of a board" , "Creditor (anag.)" , "Manager, governor" , "Creditor made to create film or play" .)