Female sex matter (7)
I believe the answer is:
shebang
'matter' is the definition.
(shebang means any matter or situation)
'female sex' is the wordplay.
'female' becomes 'she' ('she' refers to a woman).
'sex' becomes 'bang' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'she'+'bang'='SHEBANG'
Can you help me to learn more?
(Other definitions for shebang that I've seen before include "The whole ___ (entirely)" , "business" , "affair in America" , "Lot" , "Entire operation" .)