Figure skater's endlessly upset to hide Queen's disease from sheep (5,3)
I believe the answer is:
liver rot
'disease from sheep' is the definition.
'liver rot' can be an answer for 'disease' (liver rot is a kind of disease). I am not sure about the 'from sheep' bit.
'figure skater's endlessly upset to hide queen's' is the wordplay.
'figure skater's endlessly' becomes 'liver' (I can't explain this - if you can you should give a lot more credence to this answer).
'upset' says the letters should be written in reverse.
'hide' means one lot of letters goes inside another.
'queen' becomes 'r' (r is abbreviation regina. e.g. in ER ).
'to' in reverse letter order is 'ot'.
'liver'+'ot'='liverot'
'liverot' placed around 'r' is 'LIVER-ROT'.
Can you help me to learn more?
(Other definitions for liver rot that I've seen before include "it's caused by a fluke" , "consequence of fluke?" .)