Fill stomach and totally engorge, initially (4)
I believe the answer is:
sate
'fill' is the definition.
('sate' can be a synonym of 'fill')
'stomach and totally engorge initially' is the wordplay.
'initially' suggests taking the first letters.
The initial letters of 'stomach and totally engorge' is 'SATE'.
(Other definitions for sate that I've seen before include "Overfill, gorge" , "Satisfy to excess" , "Overfill, gratify" , "Satisfy to the full" , "Satisfy - surfeit" .)