Film’s way of working with struggle (5)
I believe the answer is:
movie
'film's' is the definition.
('movie' can be a synonym of 'film')
'way of working with struggle' is the wordplay.
'way of working' becomes 'mo' (I've seen this in other clues).
'with' is a charade indicator (letters next to each other).
'struggle' becomes 'vie' (I've seen this before).
'mo'+'vie'='MOVIE'
(Other definitions for movie that I've seen before include "picture" , "Flick" , "provide entertainment" , "Cinema production" , "Cinema film (mainly US)" .)