Fire in study -- get tired helping (13)
I believe the answer is:
conflagration
'fire' is the definition.
(conflagration is a kind of fire)
'study get tired helping' is the wordplay.
'study' becomes 'con' (I've seen this before).
'get tired' becomes 'flag'.
'helping' becomes 'ration' (I've seen this before).
'con'+'flag'+'ration'='CONFLAGRATION'
'in' acts as a link.
(Other definitions for conflagration that I've seen before include "Large destructive fire" , "Burning" , "Inferno" , "terrible blaze" , "result of arson" .)