Fire is in Greene novel (8)
I believe the answer is:
energise
'fire' is the definition.
('fire'->'energize' is in my internal thesaurus and 'ize'->'ise')
'is in greene novel' is the wordplay.
'in' means one lot of letters goes inside another.
'novel' indicates anagramming the letters (letters in a new or novel order).
'greene' with letters rearranged gives 'energe'.
'is' going within 'energe' is 'ENERGISE'.
(Other definitions for energise that I've seen before include "Motivate" , "To banish inertia" , "Activate" , "give vigour" , "Give power to" .)