Fired with rage (3)
I believe the answer is:
ire
'rage' is the definition.
(ire is anger)
'fired with' is the wordplay.
'with' indicates the answer is hidden within the clue.
'IRE' is hidden in the letters of 'fired'.
(Other definitions for ire that I've seen before include "Losing head" , "Fury" , "Annoyance, vexation" , "'Anger, wrath (3)'" , "passionate feeling" .)