Firm to eat and drink to get over depression (2,5)
I believe the answer is:
al dente
'firm to eat' is the definition.
(Italian cooking term meaning firm or hard)
'drink to get over depression' is the wordplay.
'drink' becomes 'ale' (type of beer).
'to get over' is an insertion indicator.
'depression' becomes 'dent' (synonyms).
'ale' placed around 'dent' is 'AL DENTE'.
'and' acts as a link.
(Other definitions for al dente that I've seen before include "Cooked so as to be firm when eaten" , "London area" , "Tel Edna (anag.); firm to bite" , "(Of pasta) still firm when bitten" , "Not soft to eat" .)