First American woman in space (4)
I believe the answer is:
ride
'first american woman in space' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for ride that I've seen before include "Journey on horse?" , "spin > lift > pedal" , "Journey as passenger" , "Travel (on a bike, perhaps)" , "Travel, by horse say" .)