First gun Laura shot, preceded by indecision originally (9)
I believe the answer is:
inaugural
'first' is the definition.
(synonyms)
'gun laura shot preceded by indecision originally' is the wordplay.
'shot' indicates an anagram.
'preceded by' is a charade indicator (letters next to each other).
'originally' indicates taking the first letters.
The initial letter of 'indecision' is 'i'.
'gun'+'laura'='gunlaura'
'gunlaura' anagrammed gives 'naugural'.
'naugural' after 'i' is 'INAUGURAL'.
(Other definitions for inaugural that I've seen before include "Marking the beginning of, eg, an institution" , "Of a speech made on taking office" , "Of a ceremony officially marking the beginning of something" , "Relating to start of job or course" , "President's address" .)