First Lady in Cleveland (3)
I believe the answer is:
eve
'first lady' is the definition.
(I've seen this before)
'in cleveland' is the wordplay.
'in' indicates a hidden word.
'EVE' is hidden in the letters of 'cleveland'.
(Other definitions for eve that I've seen before include "Night before an event" , "Woman in a happy place" , "See 13 Across" , "Day before a festival" , "Day before Christmas" .)