First of sips, enough to taste (6)
I believe the answer is:
sample
'to taste' is the definition.
(synonyms)
'first of sips enough' is the wordplay.
'first of sips' becomes 's' (1st letter of 'sips').
'enough' becomes 'ample' (I've seen this in another clue).
's'+'ample'='SAMPLE'
(Other definitions for sample that I've seen before include "Take" , "Small part used to represent the whole" , "instance" , "Small representative piece" , "Test the specimen" .)