First pairs of some home in London? (4)
I believe the answer is:
soho
'in london?' is the definition.
(area of London)
'first pairs of some home' is the wordplay.
'first pairs of' becomes 'so' (I can't explain this - if you can you should give a lot more credence to this answer).
'some home' becomes 'HO' (abbreviation for house).
'so'+'ho'='SOHO'
Can you help me to learn more?
(Other definitions for soho that I've seen before include "Theatre and night-life district of London" , "London night life area" , "Colourful district in London's West End" , "W London area" , "Central London night life district" .)