First university do held in station (9)
I believe the answer is:
uppermost
'first' is the definition.
(thesaurus)
I cannot understand how the rest of the clue works.
Can you help me to learn more?
(Other definitions for uppermost that I've seen before include "At or nearest to the top" , "Support me being on top" , "get to top" , "Highest or most prominent" , "Highest in place or rank" .)