Fixed hip secured round end of femur (9)
I believe the answer is:
ingrained
'fixed' is the definition.
(thesaurus)
'hip secured round end of femur' is the wordplay.
'hip' becomes 'in' (I've seen this in other clues).
'secured' becomes 'gained' (gaining is a kind of securing**).
'round' indicates putting letters inside.
'end of' suggests the final letters.
The last letter of 'femur' is 'r'.
'gained' placed around 'r' is 'grained'.
'in'+'grained'='INGRAINED'
(Other definitions for ingrained that I've seen before include "Deep-dyed" , "Dine in rag (anag.)" , "Deep-rooted" .)