Fled from tyranny (3)
I believe the answer is:
ran
'fled' is the definition.
(ran away)
'from tyranny' is the wordplay.
'from' indicates a hidden word.
'RAN' is hidden in the letters of 'tyranny'.
(Other definitions for ran that I've seen before include "Flowed" , "Operated; hurried" , "was in charge" , "Sped" , "Went fast" .)