Flinch from east wind on run (6)
I believe the answer is:
recoil
'flinch' is the definition.
(I've seen this before)
'east wind on run' is the wordplay.
'east' becomes 'e' ('E' can be a synonym of 'east').
'wind' becomes 'coil' (coiling is a kind of winding**).
'on' is a charade indicator (letters next to each other).
'run' becomes 'r' (cricket abbreviation).
'e'+'coil'='ecoil'
'ecoil' put after 'r' is 'RECOIL'.
'from' acts as a link.
(Other definitions for recoil that I've seen before include "Spring back suddenly as gun may when fired" , "Cringe" , "Quail is here!" , "Start back like a gun on firing" , "(As a firearm) spring back" .)