Flush loo – handle occasionally stays down (have wiped) (6)
I believe the answer is:
loaded
'flush' is the definition.
(synonyms)
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for loaded that I've seen before include "Filled with a great quantity" , "Slangily rich or with bullets in place" , "Carrying cargo; wealthy" , "Packed" , "Charged with ammunition" .)