Focus on going after US money (6)
I believe the answer is:
centre
'focus' is the definition.
(synonyms)
'on going after us money' is the wordplay.
'on' becomes 're' ('on' can be mean 'with reference to').
'going after' is a charade indicator (letters next to each other).
'us money' becomes 'cent' (US coin).
're' after 'cent' is 'CENTRE'.
(Other definitions for centre that I've seen before include "See 7" , "Midpoint" , "- forward; - punch" , "Recent (anag)" , "'Things fall apart; the ... cannot hold' (Yeats)" .)