Follow and make certain Republican is booted out (5)
I believe the answer is:
ensue
'follow' is the definition.
(ensue can mean to follow or happen as a result)
'make certain republican is booted out' is the wordplay.
'make certain' becomes 'ensure' (synonyms).
'republican' becomes 'R' (political abbreviation).
'is booted out' indicates named letters should be taken away.
'ensure' with 'r' removed is 'ENSUE'.
'and' is the link.
(Other definitions for ensue that I've seen before include "Result in a particular way" , "Happen - to come later" , "Arise" , "Occur as a result (of)" , "Happen or come about as consequence" .)