Crossword Genius

Fool is last to accept help (6)

Ross

I believe the answer is:

assist

'help' is the definition.
(assisting is a kind of helping)

'fool is last to accept' is the wordplay.
'fool' becomes 'ass' (ass is a kind of fool**).
'last to' says to take the final letters.
The last letter of 'accept' is 't'.
'ass'+'is'+'t'='ASSIST'

(Other definitions for assist that I've seen before include "Provide aid, help out" , "providing help?" , "Be useful to" , "provide backing" , "Give aid" .)

I've seen this clue in The Telegraph.
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