Fool male with ladies problem … (7)
I believe the answer is:
mislead
'fool' is the definition.
(I've seen this before)
'male with ladies problem' is the wordplay.
'male' becomes 'm' (common abbreviation).
'with' says to put letters next to each other.
'problem' is an anagram indicator.
'ladies' anagrammed gives 'islead'.
'm'+'islead'='MISLEAD'
(Other definitions for mislead that I've seen before include "Hoodwink" , "Deceive" , "Cause someone to believe something is not true" , "Take someone in the wrong direction" , "Cause someone to have a false belief" .)