Fool with strange device heading East (7)
I believe the answer is:
deceive
'fool' is the definition.
(thesaurus)
'with strange device heading east' is the wordplay.
'with' says to put letters next to each other.
'strange' indicates an anagram.
'heading east' becomes 'e' (abbreviation).
'device' is an anagram of 'deceiv'.
'deceiv' next to 'e' is 'DECEIVE'.
(Other definitions for deceive that I've seen before include "Deliberately mislead" , "Give a wrong impression to" , "Mislead, delude" , "Cheat or mislead" , "Intentionally mislead" .)