Foolishly sneer at US wine (9)
I believe the answer is:
sauternes
'wine' is the definition.
(Sauternes is an example)
'foolishly sneer at us' is the wordplay.
'foolishly' is an anagram indicator.
'sneer'+'at'+'us'='sneeratus'
'sneeratus' anagrammed gives 'SAUTERNES'.
(Other definitions for sauternes that I've seen before include "Sweet French wine" , "A sweet Bordeaux" , "Sweet white wine" .)