Fools originally in Sacramento and Palm Springs (4)
I believe the answer is:
saps
'fools' is the definition.
('sap' can be a synonym of 'fool')
I can't explain the rest of the clue.
Can you help me to learn more?
(Other definitions for saps that I've seen before include "Weakens, deprives of energy" , "Weakens, undermines" , "More than one fool" , "Coshes" , "Vital juices" .)