For the sack in shake up following initial upheaval (10)
I believe the answer is:
aftershock
'upheaval' is the definition.
(aftershock is a kind of upheaval)
'for the sack in shake up following initial' is the wordplay.
'for the sack' can be anagrammed to 'AFTERSHOCK'.
However, I am unsure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for aftershock that I've seen before include "Tremor following earthquake" , "Ground-breaking" , "that causes another little wobble" , "What might have cracked open house" , "gives one the shakes later" .)